Knowledge Base

GMP Validation
for Engineers.

Practical guides on GAMP 5, 21 CFR Part 11, PLC and SCADA engineering, OT networks, instrumentation and project delivery. Written by engineers who've done it — not by people who've only read the regulation.

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📐 GAMP 5 Theory

The V-model, risk assessment, validation lifecycle, document structure and GAMP 5 categories. Start here.

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⚖️ 21 CFR Part 11

Audit trails, electronic records, e-signatures and access control for FDA-regulated SCADA systems.

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⚙️ PLC Engineering

How to write, structure, document and validate PLC programs for GMP environments. Platform-agnostic.

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🖥️ SCADA Engineering

SCADA and HMI design, configuration and validation — historians, audit trails, user management and more.

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🌐 Network & Infrastructure

OT network design, segmentation, cybersecurity and IQ documentation for pharma automation.

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🌡️ Instrumentation

Calibration management, field instrumentation IQ documentation and sensor validation for GMP.

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📋 Project Management

How to run a pharma automation validation project as a system integrator — planning, pricing and delivery.

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🚀 Emerging Topics

Cloud SCADA, AI in GMP, digital twins, ALCOA+ data integrity and the future of computer system validation.

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QLean Automation

Everything you've read
is already in the templates.

29 production-ready GAMP 5 documents — IQ, OQ, PQ, FAT, traceability matrix, risk assessment and more. Built by engineers who understand both what the system does and what the documentation needs to demonstrate.

Get the Full Framework — €249 →
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